The Washington University Journal of Undergraduate Research

Restoring Resolution in Accelerated FLAIR MRI via U-Net Super Resolution

Abstract


Accelerated MRI scanning often results in lower resolution, introducing image distortions and loss of critical details. This study explores the application of machine learning to super-resolve Fluid-Attenuated Inversion Recovery Magnetic Resonance Imaging (FLAIR MRI) scans and restore those missing details. Specifically, we test models based on the U-Net architecture trained with two down sampling methods: removing two out of every 3 slices and linearly interpolating in image space and cropping the top and bottom thirds slices in k-space, the raw frequency data. Our experiments demonstrate that k-space down sampling consistently outperforms image-space methods in both Structural Similarity Index (SSIM) and Peak Signal-to-Noise Ratio (PSNR) metrics, while also achieving superior reconstruction of fine details. Additionally, a multi-slice input approach using three adjacent slices was shown to further improve results by providing additional spatial context. This work allows for the restoration of MRI scans collected in an accelerated manner, significantly enhancing image quality and detail for improved diagnostic confidence.

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Citation (APA)

Joo, E. (2025). Restoring resolution in accelerated FLAIR MRI via U-Net super resolution. WUJUR, 2(1), 16-19.

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Author Information

Eugene, Joo. Washington University in St. Louis.
Corresponding Author. Send correspondence to e.joo@wustl.edu.

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WUJUR thanks the anonymous Peer Reviewers who contributed to the review of this work.

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